Pharmabuzz

The current standard laboratory test for COVID-19 diagnosis is RT-PCR which identifies the viral genomic RNA has several disadvantages being time-consuming, expensive and high requirements of laboratory. A meta-analysis study by Zhang Z.L et al (2020) and Lisboa Bastos M et al (2020) reveals the diagnostic efficacy of RT-PCR test remains unclear. This leads to search of urgently identifying tests with better diagnostic accuracy.  Gold Immunochromatography assay (GICA) might be used as preferred method for obtaining accuracy and efficacy. GICA test has following advantages that it can be widely used (blood, serum and plasma can be detected); fast detection (10-15 minutes for whole process); simple operation (no professional technical personnel required for the equipment); low cost and easy to use. Through the study conducted by Shen B et al (2020); found that IgM/IgG test demonstrated high sensitivity 71.1% and specificity 96.2% in 150 suspect COVID-19 cases taking RT-PC...

COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-Co V-2) which first emerged in China on December 2019 has spread worldwide with a reported 58,03,416 confirmed cases and 3,59,791 deaths as of 29 th May 2020. The infection is typically characterized by respiratory symptoms, which indicate droplet transmission. However, many studies recently have reported the gastrointestinal symptoms observed in patients with SARS-Co V-2 infection with viral RNA present in faeces which suggests another possible route might be faecal-oral transmission. According to the review done by Tian Y et al and team suggests that an incidence of gastrointestinal symptoms which includes anorexia, diarrhea, vomiting, nausea, abdominal pain and gastrointestinal bleeding. Diarrhoea was the common gastrointestinal symptom exhibited before and after the diagnosis of the virus. Angiotensin converting enzyme 2 and virus nucleocapsid protein was detected in gastrointestinal cells. Infectio...