Posts

Casirivimab/Imdevimab - A neutralizing ANTIBODY COCKTAIL

Image
 

Can colloidal Gold Immunochromatography Assay test be alternative to RT-PCR test for diagnosis of COVID-19?

The current standard laboratory test for COVID-19 diagnosis is RT-PCR which identifies the viral genomic RNA has several disadvantages being time-consuming, expensive and high requirements of laboratory. A meta-analysis study by Zhang Z.L et al (2020) and Lisboa Bastos M et al (2020) reveals the diagnostic efficacy of RT-PCR test remains unclear. This leads to search of urgently identifying tests with better diagnostic accuracy.  Gold Immunochromatography assay (GICA) might be used as preferred method for obtaining accuracy and efficacy. GICA test has following advantages that it can be widely used (blood, serum and plasma can be detected); fast detection (10-15 minutes for whole process); simple operation (no professional technical personnel required for the equipment); low cost and easy to use. Through the study conducted by Shen B et al (2020); found that IgM/IgG test demonstrated high sensitivity 71.1% and specificity 96.2% in 150 suspect COVID-19 cases taking RT-PCR re

Possibility of COVID-19 be transmitted through oral-faecal transmission

COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-Co V-2) which first emerged in China on December 2019 has spread worldwide with a reported 58,03,416 confirmed cases and 3,59,791 deaths as of 29 th May 2020. The infection is typically characterized by respiratory symptoms, which indicate droplet transmission. However, many studies recently have reported the gastrointestinal symptoms observed in patients with SARS-Co V-2 infection with viral RNA present in faeces which suggests another possible route might be faecal-oral transmission. According to the review done by Tian Y et al and team suggests that an incidence of gastrointestinal symptoms which includes anorexia, diarrhea, vomiting, nausea, abdominal pain and gastrointestinal bleeding. Diarrhoea was the common gastrointestinal symptom exhibited before and after the diagnosis of the virus. Angiotensin converting enzyme 2 and virus nucleocapsid protein was detected in gastrointestinal cells. Infectio

WORLD MENTAL HEALTH DAY 2019

Image
Every 40 seconds, someone loses their life to suicide.   10 th October every year is celebrated as “World Mental Health Day” by the World Federation for Mental Health to raise the awareness on mental health education.  Theme for this year is: Mental Health promotion and suicide prevention . Suicidal behavior has increased gradually in all parts of the world and, in the past few decades, has reached alarming statistical levels.   This has turn to be the second leading cause of death among 15-29 year-olds globally . Every suicide is a tragedy that affects families, communities and entire countries and has long-lasting effects on the people left behind. Every year close to 800 000 people take their own life and there are many more people who attempt suicide. Another interesting fact is that, 79% of global suicides occur in low- and middle-income countries. 20% of people who suicide use pesticide self-poisoning as a way to end their life. ARE SUICIDES PREVENTABL

My Heart, Your Heart ....

Image
Image