Pharmabuzz

GOUT............. HeY! DO YOU KNOW WHAT IS MEANT BY GOUT???? It is due to accumulation of urate crystals in the synovial fluid resulting in inflammation leading to acute arthritis. Increased excretion of uric acid causes the deposition of uric acid crystals leading to stone formation with the renal damage.   Gout may be of two types: primary gout and secondary gout.  Primary Gout: is presumed to be linked to a hereditary defect in metabolism and afflicts moslty men,although women may experience the disease after menopause. Secondary Gout: is related to a failure of the kidneys to excrete uric acid products or a variety of diseases are characterised by the overproduction of certain types of body cells. Inability or failure of kidneys to excrete uric acid products can be caused by drugs including aspirin,diuretics.   Clinical Findings Of Gout: Gout attacks may be precipitated by high purine diet and increased inta...

Fungal Diseases-Clotrimazole (A curing medicine)                                               But if misused severe problems arises..... Fungal diseases or itches are found in between fingers,toes and areas which are constantly prone to sweating such as in between legs, underarm,face, hair, nails etc. Clotrimazole cream Fungal diseases are more prone to attacks and lives because of the substance keratin. Keratin, as you all is present on our body,nails,hair etc. The medicine commonly used for fungal diseases are CLOTRIMAZOLE. It is available as ointment,creams,pessaries, drops etc according to the mode of the application or region to which it is applied. USAGE /FORMULATION: Clotr imazole ( Candid 1%) creams, lotions are all available. Clotrimazole L In women, fungal diseases may appear near vaginal region- for this ...

ORPHAN DRUGS Orphan drugs are those drugs the pharmaceutical and other biotech companies are constantly researching and developing new medications to treat a rare medical condition, the condition itself is referred to as an Orphan disease . The assignment of orphan status to a disease and to any drugs developed to treat it is a matter of public policy in many countries, and has resulted in medical breakthroughs that may not have otherwise been achieved due to the economics of drug research and development . Orphan Disease: A rare disease is also referred to as an “ Orphan Disease ”, is any disease which affects a small percentage of the population. Most of the rare diseases are genetic in nature,so these are present in a person throughout in his/her life,even if the symptoms do not appear immediately. Many rare diseases appear early in life, and about 30 percent of children with rare diseases will die before reaching their fifth birthday. A rare disease occurs in less than 200,...

DRUG INFORMATION ABOUT EXENATIDE Exenatide is an injectable diabetes medicine that helps control blood sugar levels. This medication helps your pancreas produce insulin more efficiently. Exenatide is used to treat type 2 (non-insulin dependent) diabetes. Other diabetes medicines are sometimes used in combination with exenatide if needed. Prounciation: ex-N-a-tide Class: Antidiabetic agent, Incretin mimetic agent Trade name: Byetta – Injection Dosage available: solution 5 mcg/dose - Injection,                             solution   10 mcg/dose- Injection. Pharmacology: Glucagon-like peptide-1 agonist that enhances glucose-dependent insulin secretion, suppresses inappropriately elevated glucagon. SIDE EFFECTS OF EXENATIDE: For Consumers All medicines may cause side effects, but many people have no, or minor, side effects. Most COMMON side eff...

  THREE NEW DRUGS FOR TYPE 2 DIABETES Patients’ suffering from type 2 diabetes mellitus requires metformin plus something which will help to reduce the cardiovascular risk factors are some of the common aims of the drug therapy. However, the progressive impairment of both the secretion and action of insulin in the condition mean that high blood glucose concentrations usually worsen over time, so necessitating escalation of hypoglycaemic therapy. Three drugs in two new classes that act on the hormonal regulation of insulin secretion have been launched recently. They are:   (1) exenatide (Byetta – Eli Lilly)                   (2) sitagliptin (Januvia – MSD).                   (3) vildagliptin (Galvus – Novartis).

Why Cancer does not affect the Heart???? o       Heart cancers do occur, but very rarely cancer is in the abnormal, uncontrolled proliferation of cells, usually fatal. o       In general, tumors may be malignant (cancerous)-rapidly fatal if untreated or benign-causes relatively little harm. o       Cancer in any organ can be primary, originating in that organ itself or secondary when it has spread to other parts of the body. Secondary is either direct when it spreads by contiguity or indirect when the spread is through lymphatic or blood. o       Thus heart cancer (primary cardiac tumor) is cancer that arises in the heart. Cancerous tumor begin in the heart are more often sarcomas, a type of cancer that originates in the soft tissues of the body. o       The vast majority of heart tumors are benign; they include myxomas, myomas and fibromas. o    ...

CT SCANS BEST TO UNCOVER BODY PACKED DRUGS…. During 1924, Captain T W Barnard, Director, Erstwhile Institute of Radiology at the General Hospital , Madras has helped the police to locate the gold chain in the stomach of a thief by x-ray techniques. Similar many robbers and smugglers have been caught re handed by this way. Body Packing:         The US customs and Border Patrol (CBP) seize over a million pounds of drugs (mainly marijuana, cocaine, heroin and several other hallucinating drugs) annually. Eighty percent of the smugglers are caught by ‘body packing’ of these illegal narcotics. According to the May 2008 issue of Applied Radiology describes the practice of body packing as the trafficking of illicit drugs within the vagina or the gastrointestinal tract. These body packers are also known as ‘ Swallowers’, ‘Internal Carriers’, ‘Couriers’ or ‘Mules’. The most commonly used term is Mules……….…… Definition of Body packing:    ...